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A doctor in a white coat with a stethoscope points to information on a laptop screen while discussing it with a patient seated across the desk in a medical office. Cancer is a complex disease with multifactorial causes, and among these, genetics plays a significant role. Genetic mutations, both inherited and acquired during one’s lifetime,…

A Phase 1/3 Study to Evaluate Efficacy and Safety of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination With Ruxolitinib in Treatment-naïve Patients With Myelofibrosis Brief Summary: This is a global, multicenter, 2-part study to evaluate the efficacy and safety of selinexor plus ruxolitinib in JAK inhibitor (JAKi) treatment-naïve myelofibrosis (MF) participants. Key Eligibility…

A healthcare professional in a white coat and stethoscope discusses information on a laptop with an older adult wearing glasses. Receiving a cancer diagnosis and undergoing treatment is an arduous journey filled with hope and resilience. However, even after successful treatment, the fear of cancer recurrence often lingers in the minds of survivors. In this…

A Phase 2 Open-Label, Multicenter Study to Evaluate Efficacy and Safety of ZN-c3 in Subjects with High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer MOA: Azenosertib inhibits WEE1, accelerating the cell cycle and driving cancer cells with genetic instability or replication stress into apoptosis Key Eligibility Criteria: Histologically or cytologically diagnosed high-grade serous OC/FP/PPC…

Medical professional in a white coat discussing information with another person during a consultation. January is Cervical Cancer Awareness Month, a time to shed light on one of the most common cancers affecting women worldwide. Getting diagnosed with cervical cancer can be overwhelming and life-altering, causing a whirlwind of emotions and questions. In this first…